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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Dev Dyn. 2020 Oct 22;250(2):274–294. doi: 10.1002/dvdy.258

Figure 8. NCC-specific Sned1 knockout results in under-developed mandible.

Figure 8.

A-C. Examination of the mandible of a cohort of 30 adult (7 to 15-month old) mice of the Sned1NCC- transgenic line.

A. Scatterplot of PC1 and PC3 for variation in the mouse mandibular morphology. Statistical analysis was performed using a one-way non-parametric Kruskal-Wallis ANOVA.

B. Boxplot of mandibular PC1 data by mouse genotype. Numbers of mice per genotype are indicated. Statistical analysis was performed using a Tukey’s HSD test.

C. Wireframes depicting mouse mandible side view and variations as a function of genotypes. Grey dots represent the consensus cranium shape, and black dots represent the shape depicted by minimum (upper panel; representative of most Sned1WT/fl, Sned1fl/fl and Sned1WT/NCC- mice) and maximum (lower panel; representative of most Sned1NCC-/NCC- mice) PC1 range.