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. 2021 Nov 17;322(1):C24–C37. doi: 10.1152/ajpcell.00333.2021

Table 1.

Reported serum estradiol, estrone, and progesterone levels measured by GC- or LC-MS/MS from human and rodent blood

Estradiol, pg/mL Estrone, pg/mL Progesterone, pg/mL Method References
Women
 Premenopausal 15–350 17–200 1,000–45,000 LC-MS/MS (24, 25)
 Postmenopausal 1–9 5–33 LC-MS/MS (26)
  <5 yr 5 40 LC-MS/MS (27)
  >5 yr 1.3 35 (27)
Men 10–40 15–60 LC-MS/MS (24, 28)
 Rats
  Female (3–4 mo) <1–45 1–15 5–20 GC-MS/MS (21)
 Mice
  Female (3–4 mo) 1–12 1–2 10–60 GC-MS/MS (21)

<5 yr and >5 yr indicate data from women who were postmenopausal for a time less than or greater than 5 yr since their last menstrual cycle. GC, gas chromatography; LC, liquid chromatography, MS/MS, tandem mass spectrometry.