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. 2022 Jan 3;434(6):167438. doi: 10.1016/j.jmb.2021.167438

Figure 2.

Figure 2

SARS-CoV-2 genome structure and functions of viral proteins in viral replication and evasion of innate immune response. SARS-CoV-2 has a single-stranded, positive sense RNA with a cap at its 5′ end and a poly (A) tail of 30–60 nt in length at the 3′ end. The genome encodes 16 non-structural proteins (Nsp1 to Nsp16) and 4 structural proteins (S, spike; E, envelope; M, membrane and N, nucleocapsid) as well as eight accessory proteins. Their functions in viral replication and evasion of innate immune response are listed.