Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Dose calculations for aerosol droplets of various sizes to treat different target tissues.
| Target tissue | Droplet size (µm) | IC In target tissue (µg/mL) | MV Mucosal Volume (mL) | TDF Tissue Deposit Fraction | CC Colloid Concentration (µg/mL) | Inhaled dose (mL) | AD Aerosolized Dose (mL) | |
|---|---|---|---|---|---|---|---|---|
| (i) | Bronchial tree | 5 | 10 | 1 | 0.25 | 50 | 1 | 2 |
| (ii) | Bronchial tree | 5 | 40 | 1 | 0.25 | 120 | 2 | 4 |
| (iii) | Bronchial tree | 3 | 25 | 1 | 0.1 | 120 | 2.75 | 5.5 |
| (iv) | Alveoli | 3 | 10 | 10 | 0.33 | 120 | 2.75 | 5.5 |
