Table 2.
Correlation between plasma circN4BP2L2 expression level and clinicopathologic parameters of EOC (N = 126)
| N (%) | CircN4BP2L2, Mean ± SD | P-value | |
|---|---|---|---|
| Age, years old | |||
| ≤ 50 | 44/126 (35%) | 25.67 ± 13.31 | 0.06 |
| > 50 | 82/126 (65%) | 29.85 ± 27.64 | |
| Histological subtype | |||
| Serous | 73/126 (58%) | 22.33 ± 15.57 | 0.16 |
| Others | 53/126 (42%) | 24.08 ± 24.79 | |
| FIGO stage | |||
| I-II | 36/126 (29%) | 28.57 ± 15.92 | 0.04 * |
| III-IV | 90/126 (71%) | 18.94 ± 25.89 | |
| Tumor grade | |||
| G1 | 46/126 (37%) | 41.81 ± 29.98 | 0.01 * |
| G3 | 80/126 (63%) | 18.93 ± 13.75 | |
| Lymph node metastasis a | |||
| Yes | 50/112 (45%) | 18.27 ± 7.41 | 0.04 * |
| No | 62/112 (55%) | 36.24 ± 27.69 | |
| Distant metastasis | |||
| Yes | 56/126 (44%) | 16.14 ± 8.50 | 0.03 * |
| No | 70/126 (56%) | 34.68 ± 28.91 | |
Notes: a The information for lymph node metastasis was only available in 112 EOC patients
Abbreviations: N number, FIGO International Federation of Gynecology and Obstetrics, G grade, SD standard deviation