Table 3.
“Non-criteria” clinical manifestations present in the seronegative antiphospholipid syndrome group
| Clinical manifestation | |
|---|---|
| Non-obstetric (n, %) | n = 82 |
| Migraine | 23 (28.0) |
| Brain MRI white matter lesions | 21 (25.6) |
| Superficial vein thrombosis | 19 (23.2) |
| Thrombocytopenia | 17 (20.7) |
| Livedo reticularis | 10 (12.2) |
| Valvular heart disease | 8 (9.8) |
| Raynaud’s phenomenon | 6 (7.3) |
| Seizures | 6 (7.3) |
| Coombs’ positivity | 5 (6.1) |
| Memory lapses | 5 (6.1) |
| Transverse myelitis | 3 (3.7) |
| Hemolytic anemia | 3 (3.7) |
| Cognitive dysfunction | 3 (3.7) |
| Pseudo-multiple sclerosis | 3 (3.7) |
| Cardiac microvascular disease | 3 (3.7) |
| Skin ulcers | 2 (2.4) |
| APS nephropathy | 2 (2.4) |
| Livedoid vasculopathy | 1 (1.2) |
| Obstetric | n = 66 |
| Two spontaneous abortions <10 weeks | 11 (16.7) |
| Late IUGR (>34 weeks) | 5 (7.6) |
| Infertility | 4 (6.1) |
| Premature birth between 34 and 37 weeks | 3 (4.5) |
| Placental abruption | 3 (4.5) |
| ≥ 2 or more IVF failures | 2 (3.0) |
| Puerperal preeclampsia | 1 (1.5) |
| Late preeclampsia (>34 weeks) | 1 (1.5) |
| Placental hematoma | 1 (1.5) |
| Puerperal Thrombosis | 1 (1.5) |
APS Antiphospholipid syndrome, IUGR Intrauterine growth restriction, IVF In vitro fertilization, MRI Magnetic resonance imaging