Table 2.
Associations of glucocorticoid use with APOs, PB, LBW, and LFD
| APOs | PB | LBW | LFD | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| APOs (+) (n = 35) |
APOs (−) (n = 34) |
P value | PB (+) (n = 14) |
PB (−) (n = 45) |
P value | LBW (+) (n = 23) |
LBW (−) (n = 36) |
P value | LFD (+) (n = 10) |
LFD (−) (n = 49) |
P value | |
| Glucocorticoid use, n (%)## | 31 (88.6) | 25 (73.5) | 0.13 | 13 (92.9) | 36 (80.0) | 0.42 | 23 (100.0) | 26 (72.2) | < 0.01* | 10 (100.0) | 39 (79.6) | 0.19 |
| Mean glucocorticoid dose, mg/day# | 9.6 ± 5.0 | 6.6 ± 3.7 | 0.03* | 12.3 ± 5.5 | 6.7 ± 3.3 | < 0.01* | 9.5 ± 4.9 | 7.1 ± 4.2 | 0.05 | 10.0 ± 5.7 | 7.8 ± 4.3 | 0.26 |
| Increase in the glucocorticoid dose, n (%)## | 11 (31.4) | 2 (5.9) | 0.01* | 9 (64.3) | 3 (6.7) | < 0.01* | 9 (39.1) | 3 (8.3) | < 0.01* | 2 (20.0) | 10 (20.4) | 1.00 |
Values are shown as mean ± standard deviation or n (%). #Wilcoxon rank sum test; ##Fisher’s exact test; *P < 0.05. APOs adverse pregnancy outcomes, PB preterm birth, LBW low birth weight, LFD light-for-date