Table 2.

Association of 20 vitamin D genetic variants in MS GWAS dataset

SNP	Serum 25OHD GWAS			MS GWAS
	EA	NEA	EAF	Beta	SE	p val
rs8063565	C	G	0.733	− 0.002	0.019	0.928
rs11542462	A	G	0.130	0.026	0.025	0.292
rs964184	C	G	0.134	− 0.014	0.024	0.570
rs1260326	C	T	0.601	0.005	0.017	0.749
rs1800588	T	C	0.219	− 0.005	0.020	0.786
rs10908469	C	A	0.278	− 0.021	0.018	0.262
rs1532085	G	A	0.607	− 0.006	0.017	0.717
rs2131925	G	T	0.318	0.005	0.020	0.805
rs7528419	A	G	0.784	0.025	0.020	0.225
rs804281	G	A	0.576	0.028	0.017	0.098
rs532436	A	G	0.210	0.042	0.020	0.034
rs10822145	T	C	0.472	− 0.014	0.016	0.398
rs1660818	A	G	0.317	0.000	0.018	0.999
rs2276360	C	G	0.785	− 0.105	0.018	0.000
rs12317268	G	A	0.162	0.037	0.022	0.084
rs11182428	C	T	0.514	0.017	0.017	0.302
rs61003750	C	G	0.300	0.029	0.018	0.122
rs142158911	A	G	0.120	− 0.071	0.026	0.006
rs62115743	T	C	0.077	− 0.056	0.031	0.071
rs1841850	C	A	0.114	− 0.051	0.025	0.040

SNP single-nucleotide polymorphism, EA effect allele, NEA non-effect allele, EAF effect allele frequency; Beta is the regression coefficient based on the vitamin D raising effect allele, SE standard error