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. 2022 Jan 3;20:3. doi: 10.1186/s12967-021-03205-6

Table 4.

Heterogeneity test of 20 serum 25OHD genetic variants in MS GWAS dataset

Method MR-Egger intercept
Q Q_df Q_pval
MR Egger 29.446 18 0.043
Inverse variance weighted 30.614 19 0.044

p < 0.05 is set as the significant threshold. Q_pval = 0.04 represents significant heterogeneity