Fig. 5.

Aligner reproducibility. a Aligner reproducibility of SNVs. b Aligner reproducibility of insertions. c Aligner reproducibility of deletions. The bars represent average values of aligner reproducibility for the four aligners depicted by the x-axis ticks. The error sticks show standard deviation. The color legend specifies if variants were filtered by HRR or not as well as if the data are from original or confirmatory studies. d Boxplots of F-scores for SNVs (left panel), insertions (middle panel), and deletions (right panel). Results from the four aligners are plotted in different colors: black for Bowtie2, blue for BWA, red for ISAAC, and green for Stampy. F-scores from the lower bound and upper bound of variants are separated and marked at the x-axis