Table 1.

Details of input and hidden layers, as well as parameters for each architecture used

Dataset	Architecture	Nodes Layer 1	Nodes layer 2	Effective parameters (million)
	Dense	100	–	0.95 M
	Dense + pathway	100 + 92	–	0.95 M
	Dense + PPI	100 + 348	–	0.96 M
Mouse	Dense + PPI and GRN	100 + 696	–	1.01 M
	Dense + PPI and GRN	100 + 696	100	1.08 M
	Pathway	92	–	0.01 M
	Pathway	92	100	0.02 M
	Dense	100	–	1.80 M
Human	Pathway	93	–	0.01 M
	Pathway	93	100	0.02 M