Table 4.

Association of risk factors load with symptomatic intracranial hemorrhage (sICH)

No. of risk factors a	No. of subjects	No. of sICH cases	Odds ratio (95% confidence interval)
			Model 1b	Model 2c
Continuous variable (range 0–3)	1293	33	4.29 (2.73–6.74) ‡	3.76 (2.19–6.44) ‡
Categorical variable
0	435	1	1.00 (Reference)	1.00 (Reference)
1	511	4	3.42 (0.38–30.74)	2.28 (0.25–20.74)
2	272	19	28.98 (3.83–219.06) †	15.37 (1.96–120.90) †
3	58	9	69.28 (8.49–565.39) ‡	29.05 (3.13–270.11) †
P for trend			< 0.001	< 0.001

^aThree risk factors were aggregated including NIHSS on admission higher than 10, DNT >50 min, and white blood cell ≥9000/mm³

^bModel 1: Unadjusted

^cModel 2: Adjusted for coronary heart disease, neutrophils ratio, and stroke subtype

^†P < 0.05

^‡P < 0.001