Fig. 3.

Mutational and CNV profiles of co-expressed glycolysis and cholesterogenic genes across bladder cancer metabolic subtypes in the TCGA study. (A) Oncoprint depicting the distribution of SNV/indel and CNV events in the co-expressed glycolytic and cholesterogenic genes across the 4 metabolic subtypes. Fisher exact test was performed to compare the frequencies of alteration across 4 subtypes. *P < 0.05; **P < 0.01; (B) CNV variation frequency of the co-expressed glycolytic and cholesterogenic genes in the TCGA cohort. Column height represents the alteration frequency, the red dot indicates the amplification frequency, and the blue dot indicates the deletion frequency