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. 2022 Jan 3;22:2. doi: 10.1186/s12885-021-09064-0

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Immune cell infiltration and immunotherapy response across the bladder cancer metabolic subtypes. (A-B) Bar plot and histogram illustrating the distribution of 22 immune cell types estimated by CIBERSORT across the 4 metabolic subtypes. The Kruskal-Wallis test was used for comparison; (C) Immune-response rate according to metabolic subtypes in the IMvigor210 cohort; (D) Kaplan-Meier curves with log-rank test showing the overall survival of patients who received PD-L1 immunotherapy stratified by metabolic subtypes in the IMvigor210 cohort