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. 2021 Jun 30;151:106595. doi: 10.1016/j.ypmed.2021.106595

Table 1.

Underlying medical conditions potentially or definitely associated with an increased risk of severe illness from SARS-CoV-2.a

Evidence demonstrates increased risk Evidence suggests/is concerning for increased risk
Cancer Moderate-to-severe asthma
Chronic kidney disease Cerebrovascular disease
Chronic obstructive pulmonary disease Hypertension
Down syndrome Immunocompromise from bone marrow transplant, immune deficiencies, HIV, corticosteroid or other
Immunomodulator use
Heart conditions (e.g., heart failure, coronary artery disease, cardiomyopathies) Neurologic conditions such as dementia
Immunocompromise from solid organ transplant Liver disease
Obesity (BMI >30) Overweight (BMI >25 but <30 kg/m2)
Pregnancy Pulmonary fibrosis
Sickle cell disease Thalassemia
Current smoker Type I diabetes mellitus
Type II diabetes mellitus
a

From the CDC. COVID-19: People with certain medical conditions. 2020 [cited 2020 December 17]; Available from: https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/people-with-medical-conditions.html.