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. 2022 Jan 3;22:5. doi: 10.1186/s12885-021-09070-2

Table 4.

Rank of the top 20 genes in the PPI network

Rank Gene symbol Gene description Degree
1 CAT Catalase 28
2 APOB Apolipoprotein B 24
2 HP Aaptoglobin 24
2 C3 Complement component 3 24
5 FGA Fibrinogen alpha chain 23
5 AHSG α2-HS-glycoprotein 23
7 APOE Apolipoprotein E 22
7 KNG1 Kininogen 1 22
7 FGG Fibrinogen gamma chain 22
10 GC Group-specific component (vitamin D binding protein) 21
11 EHHADH Enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 19
12 TF Transferrin 18
13 A2M α2-macroglobulin 17
13 AMBP Alpha-1-microglobulin 17
13 AGT Angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 17
16 HPX Hemopexin 16
17 ITIH4 Inter-alpha-trypsin inhibitor heavy chain family, member 4 15
17 ACAA1 Acetyl-CoA acyltransferase 1 15
19 ACOX2 Acyl-CoA oxidase 2, branched chain 14
19 ECI2 Enoyl-CoA delta isomerase 2 14