Table 5.
Grade three acute toxicities
| Characteristics | Oesophagitis | Pneumonitis |
|---|---|---|
| History | 61 years old, no previous radiotherapy or thoracic surgery, no diabetes | 83 years old, no previous radiotherapy or thoracic surgery, no diabetes |
| Irradiated tumour | Parenchymal primary tumour (adenocarcinoma) | Parenchymal primary tumour (no histology) |
| Prescribed dose | 50 Gy in 5 fractions on 80% isodose, BED10 = 100 Gy | 40 Gy in 5 fractions on 80% isodose, BED10 = 72 Gy |
| OAR | Oesophagus | Heart |
| Dosimetry | Dmax oesophagus = 64,1 Gy | Dmax heart = 86 Gy; Dave homolateral lung = 4,6 Gy |
| PTV coverage | 94% | 92% |
| Paddick conformity index | 0.79 | 0.79 |
| PTV, mL | 53.5 | 42.7 |
| Planning, days | 11 | 7 |
| Time to Grade 3 toxicities, days | 11 | 42 |
BED10, biologically effective dose with α/β = 10; D, dose; Dave, average dose; Dmax, maximum dose; GTV, gross tumour volume; OAR, organ at risk; PTV, planning target volume.