Table 4.
Fatigue and genetic characteristics
| Characteristic (n = 67) | Mean (SD) | Mean rank | p-value |
|---|---|---|---|
| ABCB1 rs1045642 | |||
| CC (n = 11) | 36.36 (26.80) | 30.45 | 0.572 |
| CT (n = 27) | 34.29 (34.29) | 35.87 | |
| TT (n = 27) | 38.68 (32.67) | 31.17 | |
| COMT rs4680 | |||
| VV (n = 18) | 42.59 (35.80) | 33.06 | 0.814 |
| VM (n = 32) | 28.77 (28.77) | 32.45 | |
| MM (n = 16) | 47.92 (36.00) | 36.09 | |
| COMT rs4680 (VV & VM) vs MM | |||
| MM (n = 16) | 47.92 (36.00) | 36.09 | 0.527 |
| VV & VM (n = 50) | 40.67 (31.15) | 32.67 | |
| OPRM1 rs1799971 | |||
| AA (n = 52) | 43.16 (31.40) | 34.07 | 0.637 |
| AG (n = 14) | 39.68 (36.39) | 31.39 | |
| GG (n = 0) | – | – | |
| CLOCK rs1801260 | |||
| TT (n = 24) | 42.59 (33.20) | 28.71 | 0.933 |
| TC (n = 32) | 43.75 (30.26) | 28.34 | |
| CC (n = 0) | – | – | |
| PER2 rs934945 | |||
| GG (n = 40) | 37.78 (32.79) | 30.69 | 0.318 |
| GA (n = 23) | 48.79 (30.47) | 37.61 | |
| AA (n = 3) | 55.56 (38.49) | 39.50 | |
| PER2 rs934945 (GG & GA) vs AA | |||
| GG & GA (n = 63) | 41.80 (32.16) | 33.21 | 0.572 |
| AA (n = 3) | 55.56 (38.49) | 39.50 | |
| PER2 rs934945 GG vs (GA & AA) | |||
| GA & AA (n = 26) | 30.67 (30.67) | 37.83 | 0.132 |
| GG (n = 40) | 32.79 (32.79) | 30.69 | |
| CRY2 rs10838524 | |||
| GG (n = 22) | 44.44 (31.80) | 35.18 | 0.564 |
| AG (n = 31) | 44.09 (32.26) | 34.39 | |
| AA (n = 13) | 35.04 (34.50) | 28.54 | |
| CRY2 rs10838524 (GG & GA) vs AA | |||
| AA (n = 13) | 35.04 (34.50) | 28.54 | 0.289 |
| GG & GA (n = 53) | 44.23 (31.76) | 34.72 | |
| DRD2 rs6277 | |||
| CC (n = 9) | 59.26 (31.43) | 40.72 | 0.128 |
| CT (n = 24) | 42.59 (31.03) | 31.67 | |
| TT (n = 28) | 34.52 (31.77) | 27.30 | |
| DRD2 rs6277 (CC & CT) vs TT | |||
| TT (n = 28) | 34.52 (31.77) | 27.30 | 0.126 |
| CC & CT (n = 33) | 47.14 (31.55) | 34.14 | |