Figure 4.

Lactate-to-pyruvate concentration ratio (L/P) in central mixed venous ($\overline{\upsilon }$) and arterial blood (a), of anesthetized rats studied under control (Con), exogenous lactate infusion (lactate clamp, LC) and epinephrine infusion (Epi). Values are expressed as means ± SD. Metabolic activity of the lung parenchyma in converting pyruvate to lactate is apparent under all conditions studied. ^Significantly different than the corresponding trial $\overline{\upsilon }$, P < 0.05. From Ref. 52. Mixed venous and arterial lactate/pyruvate ratios are different clearly indicating roles of heart and lung parenchyma.