Table 6.
Comparison between studies with CMR-derived normal reference values
| Study (Author, Journal Year) | Sample Size (n =) | Age (years) | Ethnicity | % Female representation (male:female) | Contouring Method | Mean LVEDV indexed to BSA (ml/m2) | Mean LVEF (%) |
|---|---|---|---|---|---|---|---|
| Current study, Luu et al. 2021 | 3206 | 35–75 | Multi-ethnic | 65% (1126:2080) | Inclusion of papillary muscle in LV mass |
Female: 66 Male: 74 |
Female: 65 Male: 62 |
| Petersen et al. JCMR 2017 | 800 | 45–74 | All Caucasians | 54% (368:432) | Inclusion of papillary muscle in LV volume |
Female: 74 Male: 85 |
Female: 61 Male: 58 |
| Lei et al., JMRI 2017 | 120 | 23–83 | All Han Chinese | 50% (60:60) | Inclusion of papillary muscle in LV volume |
Female: 68.7 Male: 76.5 |
Female: 67.1 Male: 64.6 |
| Le et al., JCMR 2016 | 180 | 20–69 | All Singaporean Chinese | 49% (91:89) | Inclusion of papillary muscle in LV mass |
Female: 71 Male: 79 |
Female: 62 Male: 58 |
| Yeon et al., JMRI 2015 | 852 | 38–88a | Most Caucasians | 60% (512:340) | Inclusion of papillary muscle in LV volume |
Female: 62 Male: 71 |
Female: 60.6 Male: 58.6 |
| Natori et al., AJR 2006 | 800 | 45–84 | Multi-ethnic | 50% (400:400) | Inclusion of papillary muscle in LV volume |
Female: 64.5 Male: 73.9 |
Female:71.8 Male: 67.2 |
| Maceira et al., JCMR 2006 | 120 | 20–80 | Not mentioned | 50% (60:60) | Inclusion of papillary muscle in LV mass |
Female: 75 Male: 80 |
Female: 67 Male: 67 |
| Hudsmith et al., JCMR 2005 | 108 | 21–68 | Not mentioned | 42% (63:45) | Inclusion of papillary muscle in LV mass |
Female: 78 Male: 82 |
Female: 69 Male: 69 |
| Alfakih et al., JMRI 2003 | 60 | 20–65 | Not mentioned | 50% (30:30) | Inclusion of papillary muscle in LV mass |
Female: 77.7 Male: 82.3 |
Female: 64.0 Male: 64.2 |
| Salton et al., JACC 2002 | 142 | 38–72 | Not mentioned | 56% (63:79) | Inclusion of papillary muscle in LV volume |
Female: 49.8 Male: 57.6 |
Female: 70 Male: 69 |
aAge range not reported in original publication, but study population clarified in the source by Oyama et al. 2008. “Differential Impact of Age, Sex, and Hypertension on Aortic Atherosclerosis.” Arteriosclerosis, Thrombosis, and Vascular Biology 28 (1): 155–59
LV left ventricular; LVEDV left ventricular end-diastolic volume; BSA body surface area; LVEF left ventricular ejection fraction