Table 3.
Univariate and multivariable Cox regression analysis of prognostic factors for all–cause mortality
| Characteristic | Cox Univariate | Cox Multivariate | ||||
|---|---|---|---|---|---|---|
| HR (95% CI) | P–value | HR (95% CI) | P–value | HR (95% CI) | P–value | |
| Galectin–3 (> 8.65 versus ≤8.65 ng/ml) | 1.92 (1.17–3.17) | 0.01 | 1.59 (0.96–2.65) | 0.07 | – | – |
| Galectin–3 (continuous variable) | 0.99 (0.97–1.02) | 0.70 | – | – | 0.99 (0.96–1.03) | 0.74 |
| Age (years) | 1.07 (1.05–1.08) | P < 0.01 | 1.06 (1.04–1.07) | P < 0.01 | 1.06 (1.04–1.08) | P < 0.01 |
| ESRD due to diabetes (yes versus no) | 2.67 (2.00–3.57) | P < 0.01 | 2.20 (1.34–3.59) | P < 0.01 | 2.12 (1.30–3.46) | P < 0.01 |
| ESRD due to glomerulonephritis (yes versus no) | 0.33 (0.23–0.47) | P < 0.01 | ||||
| ESRD due to hypertension (yes versus no) | 1.50 (1.08–2.10) | 0.02 | ||||
| Hemoglobin (g/l) | 0.99 (0.98–1.00) | 0.02 | ||||
| Albumin (g/l) | 0.85 (0.81–0.89) | P < 0.01 | 0.93 (0.88–0.99) | 0.01 | 0.93 (0.88–0.98) | 0.01 |
| Dialysis dose (spKt/V) | 0.45 (0.24–0.85) | 0.01 | 0.38 (0.19–0.77) | P < 0.01 | 0.37 (0.18–0.75) | P < 0.01 |
| Alkaline phosphatase (u/l) | 1.003 (1.001–1.004) | P < 0.01 | 1.004 (1.002–1.005) | P < 0.01 | 1.004 (1.002–1.005) | P < 0.01 |
| Sodium (mmol/l) | 0.93 (0.89–0.97) | P < 0.01 | ||||
Abbreviations: CI confidence interval, ESRD end–stage renal disease, HR hazard ratio