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. Author manuscript; available in PMC: 2022 Jan 3.
Published in final edited form as: Cancer Res. 2019 Dec 10;80(4):857–867. doi: 10.1158/0008-5472.CAN-19-1991

Figure 3. Missense alleles classified as null, hypomorphic or wildtype based on ICL damage induced cell killing.

Figure 3.

Clonogenic growth assays of independent HeLa clones after exposure to increasing concentrations of MMC and cisplatin. Data presented are the average of three replicates with error bars indicating one standard deviation. Cisplatin experiments were performed simultaneously with a single BRIP1+/+. +/− and −/− clone for control.