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. Author manuscript; available in PMC: 2022 Jan 3.
Published in final edited form as: Cancer Res. 2019 Dec 10;80(4):857–867. doi: 10.1158/0008-5472.CAN-19-1991

Figure 5. Occurrence of functionally characterized variants in clinical testing.

Figure 5.

Q740H and A745T account for a majority of the wildtype alleles (green) identified. P47A was the most common hypomorph allele (orange) detected. Null alleles (red) were seen at lower frequencies. Helicase domain motifs: III (610-624); IV (689-710); V (748-775); VI (819-836).