Skip to main content
. Author manuscript; available in PMC: 2022 Jan 3.
Published in final edited form as: Cell Rep. 2021 Nov 30;37(9):110076. doi: 10.1016/j.celrep.2021.110076

Figure 2. Glutamate post-synapse PIN alterations following chemical LTP in cultured cortical neurons.

Figure 2.

(A) PCA showing separation of aCSF control (C, red) and cLTP (L, blue).

(B) Heatmap of all PiSCES that were ANC∩CNA significant for the cLTP versus control comparison, meaning they are significant by the ANC statistical test and belong to a CNA module that is significantly correlated with cLTP treatment. Each column represents a single biological replicate, N = 8, and each box represents a single PiSCES measurement.

(C) Graphs comparing the log2 fold change of two example PiSCES, Homer1_SynGAP and PIKE_PIKE, that were ANC∩CNA-significant in both cLTP and 15-min GLUT experiments. Points represent a ratio between the aCSF condition and the respective stimulation, N = 4 per treatment.

(D) x-y plot comparing the log2 fold change (FC) of all PiSCES that were ANC∩CNA significant for either the cLTP experiment (blue), the 15 min glutamate time point (red), or both experiments (purple).