Table 2.
Effect of probiotics supplementation at T3, based on route of delivery.
| Effect of probiotics supplementation based on route of delivery | ||||||
|---|---|---|---|---|---|---|
| Vaginal delivery | Caesarean section | |||||
| Probiotic Median (IQR, range) N = 9 |
Placebo Median (IQR, range) N = 6 |
P value | Probiotic Median (IQR, range) N = 9 |
Placebo Median (IQR, range) N = 12 |
P value | |
| Sum of relative abundance of potentially pathogenic families at T3 | 49.1 (25.9–67.4) | 74.2 (49.6–89.8) | 0.37 | 52.5 (44.2–67.7) | 58.4 (51.2–95.9) | 0.39 |
| Relative abundance of Bifidobacteriaceae at T3 | 42.8 (23.7–55.2) | 0.05 (0.03–12.9) | 0.049 | 33.7 (28.9–45.4) | 0.03 (0.01–1.51) | 0.001 |
| Total SCFA levels at T3 (μg per gram of wet faeces) | 2254 (IQR: 1915–2668); range: 1243–5152 | 1529 (IQR: 1349–2208); range: 723–2647 | 0.18 | 2598 (IQR: 1588–2786); range: 1399–3388 | 1725 (IQR: 1092–2135); range: 426–2723 | 0.034 |
Bold values indicate statistical significance p < 0.05.
IQR interquartile range, SCFA short-chain fatty acid, T3 two weeks after commencing supplementation.