Table 9.

Hydrophobic moment, net charge, lipid-binding discrimination factor, Boman, and Wimley–White index of designed AntiSCV2 and AntiIAV peptides

Peptide category	Peptide name	Hydrophobic moment	Net charge	Lipid-binding discrimination factor	Boman index (kcal mol−1)	Wimley–White index
Wild HR2 sequence from SCV2		0.43	− 1	0.08	1.95	10.54
Designed Anti-SCV2 peptides	AntiSCV2P1	0.57	1	0.87	2.05	14.60
	AntiSCV2P2	0.58	1	0.87	2.39	12.39
	AntiSCV2P3	0.48	0	0.45	1.67	12.27
	AntiSCV2P4	0.50	0	0.48	2.01	12.27
	AntiSCV2P5	0.56	0	0.52	1.37	12.21
	AntiSCV2P6	0.55	1	0.85	2.80	13.57
	AntiSCV2P7	0.54	1	0.84	2.25	12.39
	AntiSCV2P8	0.58	− 1	0.21	2.34	13.78
	AntiSCV2P9	0.57	− 1	0.21	2.43	13.88
Wild fusion peptide sequence from IAV		0.53	− 2	0.16	− 1.19	− 3.89
Designed Anti-IAV peptides	AntiIAVP1	0.56	0	0.53	− 1.33	− 4.21
	AntiIAVP2	0.67	2	1.29	− 0.35	− 0.35
	AntiIAVP3	0.61	1	0.91	− 0.87	− 1.90
	AntiIAVP4	0.64	1	0.94	− 1.03	− 2.63
	AntiIAVP5	0.64	− 1	0.28	− 1.61	− 3.54
	AntiIAVP6	0.55	0	0.52	− 1.40	− 3.42
	AntiIAVP7	0.67	2	1.29	− 0.44	0.44
	AntiIAVP8	0.64	− 1	0.27	− 1.70	− 2.75