Fraser 1980.
Methods | Allocation: Randomised controlled trial, randomisation procedure not described and allocation concealment unclear; Duration: not specified; patient and outcome assessor blinding seems appropriate; no follow‐up period; Intention‐to‐treat analysis not mentioned, possible 4 patients dropped‐out, authors seem to have used an end‐point analysis; | |
Participants | Diagnosis: Depressive illness, based on Feigner criteria; Age 64 ‐ 86 years; N = 33, 5 participatns dropped‐out; Sex: 8 M, 25 F; Inclusion criteria: depression of a least a month duration, dementia was not an exclusion criterium, other inclusion criteria not specified. | |
Interventions | Unilateral versus bilateral ECT; no information is provided on the adequacy of seizures or the method by which seizures were induced; unilateral ECT n = 13 bilateral ECT n = 16 | |
Outcomes | Mood change: Hamilton Rating Scale (HAM‐D) and the Nursus' Observation scale for Inpatient evaluation; Cognitive side‐effects: the Wechsler Memory Scale Other side‐effects by questionnaire |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Unclear risk | B ‐ Unclear |