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. 2003 Apr 22;2003(2):CD003593. doi: 10.1002/14651858.CD003593

Fraser 1980.

Methods Allocation: Randomised controlled trial, randomisation procedure not described and allocation concealment unclear; 
 Duration: not specified;
 patient and outcome assessor blinding seems appropriate; 
 no follow‐up period; Intention‐to‐treat analysis not mentioned, possible 4 patients dropped‐out, authors seem to have used an end‐point analysis;
Participants Diagnosis: Depressive illness, based on Feigner criteria;
 Age 64 ‐ 86 years;
 N = 33, 5 participatns dropped‐out; 
 Sex: 8 M, 25 F;
 Inclusion criteria: depression of a least a month duration, dementia was not an exclusion criterium, other inclusion criteria not specified.
Interventions Unilateral versus bilateral ECT; no information is provided on the adequacy of seizures or the method by which seizures were induced;
 unilateral ECT n = 13
 bilateral ECT n = 16
Outcomes Mood change: Hamilton Rating Scale (HAM‐D) and the Nursus' Observation scale for Inpatient evaluation;
Cognitive side‐effects:
 the Wechsler Memory Scale
Other side‐effects by questionnaire
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear