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. 2003 Apr 22;2003(2):CD003593. doi: 10.1002/14651858.CD003593

Kellner 1992.

Methods Allocation: Randomised controlled trial, randomisation procedure not described and allocation concealment unclear;
 Duration: not described;
 No follow‐up period;
 Patient blinding: not possible;
 Outcome blinding: procedure not described, bias seems possible, cannot be excluded;
 Intention to treat analysis not mentioned, none of the participants dropped out of treatment.
Participants Diagnosis: DSM‐III criteria for major depression;
 Age 53‐87 years;
 participants had been referred for ECT treatment, no information is provided on earlier antidepressant treatment in any of the participants;
 N = 15;
 Sex: 11M and 4F
Interventions ECT once a week versus three‐times‐weekly ECT;
 bilateral treatment in all participants;
 method of seizure induction adequately described
Outcomes Mood change: Hamilton Rating Scale for Depression (HAM‐D), the Beck Depression Inventory (BDI), the Clinical Global Improvement Scale (CGI) and the Brief Psychiatric Rating Scale (BPRS)
Cognitive side effects: Mini Mental Status Examination (MMSE) and the Wechsler Memory Scale‐Revised (WMS‐R)
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Unclear risk B ‐ Unclear