Kellner 1992.
Methods | Allocation: Randomised controlled trial, randomisation procedure not described and allocation concealment unclear; Duration: not described; No follow‐up period; Patient blinding: not possible; Outcome blinding: procedure not described, bias seems possible, cannot be excluded; Intention to treat analysis not mentioned, none of the participants dropped out of treatment. | |
Participants | Diagnosis: DSM‐III criteria for major depression; Age 53‐87 years; participants had been referred for ECT treatment, no information is provided on earlier antidepressant treatment in any of the participants; N = 15; Sex: 11M and 4F | |
Interventions | ECT once a week versus three‐times‐weekly ECT; bilateral treatment in all participants; method of seizure induction adequately described | |
Outcomes | Mood change: Hamilton Rating Scale for Depression (HAM‐D), the Beck Depression Inventory (BDI), the Clinical Global Improvement Scale (CGI) and the Brief Psychiatric Rating Scale (BPRS) Cognitive side effects: Mini Mental Status Examination (MMSE) and the Wechsler Memory Scale‐Revised (WMS‐R) |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Unclear risk | B ‐ Unclear |