Table 3.

Univariate and Multivariate Analysis of Clinicopathological Characteristics Affecting Prognosis of Patients with PC

Characteristics	Univariate			Multivariate
	HR	95% CI	p value	HR	95% CI	p value
ACTL6A
Low		Ref			Ref
High	1.899	1.056–3.415	0.032	1.810	1.010–3.243	0.046
Age(years)
<65		Ref
≥65	1.053	0.600–1.848	0.857
Sex
Male		Ref
Female	0.646	0.365–1.141	0.132
Tumor site
Head		Ref
Othera	0.736	0.422–1.284	0.281
Grade
Well/moderately		Ref			Ref
Poorly/undifferentiated	2.198	1.231–3.924	0.008	2.021	1.127–3.624	0.018
T stage
T1+T2		Ref			Ref
T3+T4	1.737	0.973–3.103	0.062	1.575	0.880–2.819	0.126
N stage
N0		Ref
N1+N2	1.442	0.816–2.550	0.208
M stage
M0		Ref
M1	2.205	0.673–7.221	0.191
TNM stage
I		Ref
II–IV	1.759	0.853–3.626	0.126
LVSI
No		Ref
Yes	1.434	0.822–2.501	0.204

Note: ^aPancreatic body and tail.

Abbreviations: ACTL6A, actin-Like 6A; PC, pancreatic cancer; LVSI, lymphovascular space invasion.