Fig. 3. Antigenic cartography of convalescent and vaccinee sera against WT, Delta and Omicron.

Antigenic maps were separately generated from convalescent (left panel), 2^nd vaccination (middle panel) or 3^rd vaccination (right panel) sera. Convalescent sera are shown in diamonds as follows: B.1 (dark green), B.1.2 (light green), B.1.1.7 (purple), B.1.351 (brown), AY variants (light blue), and B.1.617.2 (dark blue). Gray diamonds correspond to post-vaccination sera. Each grid square corresponds to 2-fold dilution in the neutralization assay. Black squares correspond to WT variant. Blue triangles correspond to Delta variant. Red circle corresponds to Omicron variant.