Figure 1. Neutralization of D614G and B.1.429 pseudoviruses by serum from individuals with different exposures.

Plot of 50% and 90% pseudovirus neutralization titers (NT₅₀ and NT₉₀) of serum samples obtained from donors with the indicated infection and/or vaccination exposures. Grey lines connect neutralization titer values for D614G (black dots) and B.1.429 (blue dots) pseudoviruses within each individual serum sample. Geometric mean neutralization titers for each serum group are marked with red lines and fold-change in NT50 and NT90 between D614G and B.1.429 pseudoviruses is shown along with P-value. Dark grey shading marks the interquartile range of titer values in each group and light grey shading marks the 10^th-90^th percentile of the range. P-values were calculated with a Wilcoxon matched-pairs signed-rank test.