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. 2021 Dec 20;17(12):e1009684. doi: 10.1371/journal.pcbi.1009684

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© 2021 Paluoja et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — Z-scores of known trisomy samples at sequencing depths of 20M RPS (A), 15M RPS (B), 10M RPS (C), 5M RPS (D), 2.5M RPS (E), and 1.25M RPS (F) are shown. Undetected (false negative) trisomies falling below the Z_t cut-off thresholds (black dashed line in each graph) are represented as black triangles.