Table 2.
TAMs targeting peptides.
| Peptide | Sequence | Target | Function | References |
|---|---|---|---|---|
| M2pep | YEQDPWGVKWWY-OH | Murine CD45+F4/80+CD301+TAMs | Targeting | (195) |
| Cyclic M2pep(RY) | CGYEQDPWGVRYWYGC-OH | Murine CD45+F4/80+CD301+TAMs | Targeting | (203, 204) |
| Melittin | GIGAVLKVLTTGLPALISWIKRKRQQ-NH2 | CD206 TAMs | Targeting | (197) |
| “UNO” peptide | CSPGAKVRC-OH | CD206 TAMs | Targeting | (196) |
| RP-182 peptide | KFRKAFKRFF-OH | CD206 TAMs | Targeting; M2 macrophages apoptosis; M2 macrophages repolarization towards M1 |
(198) |
| T4 | NLLMAAS-OH | Tie2+ TAMs and endothelial cells. | Targeting; Blocks Tie2/Ang1 |
(205) |
| IL4RPep-1 | CRKRLDRNC-OH | IL-4R+ TAMs and tumor cells. | Targeting | (199) |
| Pep-20 | AWSATWSNYWRH-NH2 | CD47 | Targeting; Block CD47/SIRPα |
(201) |
| Pep-20-D12 | a w s ATWSNY w r h-NH2* | CD47 | Targeting; Block CD47/SIRPα |
(201) |
| CRV | CRVLRSGSC-OH | TAMs retinoid X receptor beta | Targeting | (202) |
*Lower case letters represent D-amino acids.