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. 2021 Dec 20;8:780621. doi: 10.3389/fmolb.2021.780621

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Copyright © 2021 Lu, Su, Wang, Zhang, Ma, Li and Qiu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characteristics of the detected tsRNAs in nasopharyngeal carcinoma and healthy controls. (A) Length distribution of the detected tsRNAs. x-axis, the length of the detected tsRNAs; y-axis, the abundance of tsRNAs classified by different lengths. (B) Length of tsRNAs in NPC tumor tissues and matched normal tissues mainly ranged from 14 to 40 nt **p < 0.01, ****p < 0.0001. (C) Reads number of the source of tRFs and tiRNAs (mature tRNA and precursor tRNA). (D–E) Distribution of source tRNAs in healthy controls and nasopharyngeal carcinoma. (F) Circos plot of detected tsRNAs on human chromosomes (visualize only part of the data). Abbreviations: T, tumor specimens; N, normal specimens.