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. 2021 Oct;32(10):2529–2541. doi: 10.1681/ASN.2021010101

Figure 3.

Figure 3.

p-CREB regulates ADPKD-associated genes. (A) Schematic overview of transcriptomic analysis in DBA-positive cells from early-onset mice at P29. (B) Heatmap of differentially expressed genes in DBA-positive cells from the indicated groups. (C) Violin plots showing the relative fragments per kilobase of transcript per million mapped reads (FPKM) values of upregulated genes and downregulated genes in DBA-positive cells from the indicated groups. (D) Identification and function enrichment analysis of CREB direct target genes. (E) Quantitative PCR validation of representative genes in DBA-positive cells from the indicated groups. ***P<0.001.