Table 3.

Key elements to be included in a manuscript reporting an MR study

Elements
1. Rationale for the MR analysis
2. Description and justification for the data used
3. Description and justification of the genetic variants used
4. Discussion of whether the genetic variants are likely to satisfy the three instrumental variable assumptions
5. Graphical presentation of the data, such as scatter plots of the genetic associations when several instruments are evaluated
6. Results of additional testing to assess the robustness of the main findings

Adapted from reference 24.