Fig. 2.

BioDynaMo’s layered architecture. BioDynaMo is predominantly executed on multi-core CPUs, is able to offload computations to the GPU, and supports Linux and MacOS operating systems. BioDynaMo provides a rich set of low- and high-level features commonly required in agent-based models. On top of these generic features, BioDynaMo offers model building blocks to simplify the development of a simulation. Even if BioDynaMo does not provide the required building blocks, users still benefit from all generic agent-based features (illustrated by the vertical extension of the ‘Simulation’ layer)