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. 2021 Oct 2;38(2):520–526. doi: 10.1093/bioinformatics/btab686

Table 1.

List of normalization methods that were evaluated

Normalization Method
• Median normalization
• Q50 and Q75: 50% and 75% quantile normalization
• SQUA: smooth quantile normalization (Hicks, 2018)
• UQUA: upper quartile normalization (Bullard, 2010)
• MRN: median ratio normalization (Maza, 2013)
• TMM: trimmed mean of the M-values (Robinson and Oshlack, 2010; Tarazona, 2011, 2015)