Table 1. Summary of cases with clinico-pathological details.

	Case 1	Case 2	Case 3	Case 4
Age	50	72	40	36
Co-morbidity	Nil	Hypertension	Hypertension	Nil
Smoking	Nil	Nil	Nil	Nil
Breast size	32B	34C	36C	30AA
Presentation	Screen detected	Symptomatic (lump)	Symptomatic (lump)	Symptomatic (single duct nipple discharge)
Family history	Nil	Nil	Nil	Nil
Radiological size	Bifocal 24 and 15 mm (total extent 54*30 mm)	Unifocal (Mammogram and USS occult), MRI 26 mm)	Unifocal 35 mm	Radiologically occult
Pre-op. histology	Grade 2 IDC with IG DCIS	Grade 2 ILC with HG DCIS	Grade 3 IDC with HG DCIS	Epithelial cells on nipple discharge cytology
IHC	ER8, Her2 negative	ER8, Her2 negative	ER8, Her2 negative	ER8, Her2 negative
Post op. histology	Grade 2 IDC 25 and 16 mm with IG DCIS	Grade 2 ILC 26 and 8 mm with HG DCIS	Grade 3 IDC 35 mm with extensive HG DCIS, separate medial shave had more DCIS < 1 mm to final margin	Grade 1 mucinous 6 mm with HG DCIS on duct excision with margins involving DCIS, G2 mucinous 3 mm with HG DCIS on therapeutic surgery
Lymphovascular invasion	No	No	Yes	No
Sentinel node biopsy	1/1 (macrometastasis, 6 mm, no ECS)	1/2 (macrometastasis, 10 mm, no ECS)	1/1 (micrometastasis, 1 mm, no ECS)	0/1
TNM classification	pT2N1a(sn)	pT2N1a(sn)	pT2N1mi(sn)	pT1bN0(sn)

IDC, Invasive ductal carcinoma, no special type; ILC, Invasive lobular carcinoma; DCIS, Ductal carcinoma in-situ; IG, Intermediate grade; HG, High grade; ECS, Extracapsular spread; USS, Ultrasound scan; IHC, Immunohistochemistry