Table 1.
Characteristics of participants and non-participants
| Participants (N ≈ 151)a | Non-participants (N = 223)b | p | |
|---|---|---|---|
| Sociodemographic characteristics | |||
| Age (years, mean ± SD (range)) | 24.1 ± 3.6 (18–30) | 24.0 ± 3.4 (18–30) | 0.659 |
| Sex (female, N(%)) | 61.6 (93) | 40.8 (90) | ≤ 0.001 |
| Partner status N(%) | |||
| Yes | 51.0 (75) | ||
| No | 49.0 (72) | ||
| Employment status N(%) | |||
| Paid occupation | 70.9 (105) | ||
| Without paid occupation | 29.1 (43) | ||
| Attained educationc N(%) | |||
| Low | 19.3 (28) | ||
| Middle | 48.3 (70) | ||
| High | 32.4 (47) | ||
| Current educationc N(%) | |||
| Low | 3.1 (2) | ||
| Middle | 27.7 (18) | ||
| High | 69.2 (45) | ||
| Medical characteristics | |||
| Age at diagnosis (years, mean ± SD (range)) | 10.5 ± 4.5 (0.4–17) | 10.6 ± 4.5 (0–18) | 0.756 |
| Time since diagnosis (years, mean ± SD (range)) | 13.6 ± 3.8 (6–27) | 13.5 ± 3.7 (6–28) | 0.652 |
| Diagnosis N(%) | |||
| Hematologic cancers | 66.9 (101) | 61.7 (142) | 0.119 |
| CNS tumors | 8.6 (13) | 9.9 (22) | 0.358 |
| Solid tumors | 24.5 (37) | 28.3 (63) | 0.173 |
| Recurrence N(%) | 13.9 (21) | ||
| Treatmentd N(%) | |||
| Surgery (S) | 61.6 (93) | 63.7 (142) | 0.323 |
| Chemotherapy (CT) | 95.4 (144) | 95.5 (213) | 0.522 |
| Radiotherapy (RT) | 37.1 (56) | 35.0 (78) | 0.323 |
| SCT/BMT | 7.3 (11) | 13.5 (30) | 0.012 |
| Treatment combinationse N(%) | |||
| CT only | 32.5 (49) | ||
| CT + RT | 6.0 (9) | ||
| RT + S | 4.6 (7) | ||
| CT + S | 30.5 (46) | ||
| CT + S + RT | 26.5 (40) | ||
| Participants (N ≈ 151) | General populationf,g | p | |
| Psychosocial well-being mean ± SD (range) / % (N) | |||
| PedsQL-YA physical | 80.2 ± 19.7 (21.9–100) | 87.1 ± 16.0 | ≤ 0.001 |
| PedsQL-YA social | 82.1 ± 20.0 (10.0–100) | 87.2 ± 14.5 | 0.001 |
| PedsQL-YA school/work | 76.8 ± 19.1 (5.0–100) | 82.3 ± 15.7 | ≤ 0.001 |
| HADS anxiety (≥ 8) | 30.2 (45) | 18.8 (42) | 0.017 |
| HADS depression (≥ 8) | 12.8 (19) | 7.6 (17) | 0.134 |
| CIS-20R fatigue severity (≥ 35) | 36.2 (54) | 20.8 (55) | ≤ 0.001 |
aData incomplete for some participants. The numbers in the table are based on the records with complete data per variable
bNo medical information available from 4 non-participants
cLow = primary education, lower vocational education, lower and middle general secondary education; middle = middle vocational education, higher general secondary education, pre-university education; high = higher vocational education, university
dMore than one category possible
eTreatments for primary tumor and (if applicable) recurrence(s)
fPedsQL-YA N = 649; HADS N = 224; CIS-20-R N = 264
gStudy reported elsewhere[25]
Abbreviations: PedsQL-YA Pediatric Quality of Life–Young Adults; HADS Hospital Anxiety and Depression Scale; CIS-20R Checklist Individual Strength Revised