Table 3.
Multivariate logistic regression models for any support needs on the eight domains with sociodemographic and medical characteristics as well as psychosocial well-being as independent variables
| Physical | Social-emotional | Relationships/sexuality | Fertility | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| (69.5%, N = 105)a | (53.6%, N = 81) a | (34.4%, N = 52) a | (68.2%, N = 103) a | ||||||||||||||
| OR | 95%CI | p | OR | 95%CI | p | OR | 95%CI | p | OR | 95%CI | p | ||||||
| Socioeconomic | |||||||||||||||||
| Sex (ref = male) | 1.58 | [0.73;3.42] | 0.249 | - | - | - | 1.74 | [0.76;3.98] | 0.189 | 4.26 | [1.94;9.38] | ≤ 0.001 | |||||
| Attained Education (ref = low) | |||||||||||||||||
| Middle | - | - | - | - | - | - | - | - | - | 2.42 | [0.93;6.28] | 0.070 | |||||
| High | - | - | - | - | - | - | - | - | - | 8.43 | [2.55;27.82] | ≤ 0.001 | |||||
| Medical | |||||||||||||||||
| Age at diagnosis | - | - | - | - | - | - | - | - | - | - | - | - | |||||
| Time since diagnosis | - | - | - | - | - | - | - | - | - | - | - | - | |||||
| Diagnosis (ref = hematological) | |||||||||||||||||
| CNS tumor | - | - | - | - | - | - | - | - | - | - | - | - | |||||
| Solid tumor | - | - | - | - | - | - | - | - | - | - | - | - | |||||
| Recurrence | - | - | - | - | - | - | 2.62 | [0.94;7.32] | 0.067 | - | - | - | |||||
| Surgery (yes/no) | - | - | - | - | - | - | - | - | - | - | - | - | |||||
| Chemotherapy (yes/no) | - | - | - | - | - | - | - | - | - | - | - | - | |||||
| Radiotherapy (yes/no) | - | - | - | - | - | - | - | - | - | - | - | - | |||||
| Psychosocial | |||||||||||||||||
| PedsQL-YA Physical Functioning (0–100) | - | - | - | 1.03 | [1.0;1.06] | 0.065 | - | - | - | - | - | - | |||||
| PedsQL-YA Social Functioning (0–100) | 0.98 | [0.96;1.01] | 0.135 | 0.91 | [0.88;0.95] | ≤ 0.001 | 0.98 | [0.96;1.0] | 0.021 | - | - | - | |||||
| PedsQL-YA Work/School Functioning (0–100) | - | - | - | 0.99 | [0.96;1.02] | 0.574 | - | - | - | - | - | - | |||||
| HADS (sub)clinical anxiety (≥ 8) | 4.29 | [1.36;13.53] | 0.013 | 5.66 | [2.05;15.65] | 0.001 | 2.24 | [0.92;5.44] | 0.075 | - | - | - | |||||
| HADS (sub)clinical depression (≥ 8) | - | - | - | 0.44 | [0.08;2.26] | 0.322 | 1.04 | [0.30;3.64] | 0.954 | - | - | - | |||||
| CIS-20R severe fatigue (≥ 35) | 2.11 | [0.81;5.50] | 0.126 | - | - | - | - | - | - | - | - | - | |||||
| Lifestyle and health | School and work | Future perspective | Insurance and mortgage | ||||||||||||||
| (76.2%, N = 115) a | (29.8%, N = 45) a | (49.0%, N = 74) a | (54.3%, N = 82) a | ||||||||||||||
| OR | 95%CI | p | OR | 95%CI | p | OR | 95%CI | p | OR | 95%CI | p | ||||||
| Socioeconomic | |||||||||||||||||
| Sex (ref = male) | 2.39 | [1.01;5.66] | 0.047 | - | - | - | 1.96 | [0.86;4.49] | 0.110 | 1.76 | [0.81;3.84] | 0.152 | |||||
| Attained education (ref = low) | |||||||||||||||||
| Middle | 2.14 | [0.77;5.93] | 0.146 | - | - | - | - | - | - | - | - | - | |||||
| High | 6.90 | [1.89;25.19] | 0.003 | - | - | - | - | - | - | - | - | - | |||||
| Medical | |||||||||||||||||
| Age at diagnosis | - | - | - | - | - | - | - | - | - | 1.10 | [1.02;1.20] | 0.019 | |||||
| Time since diagnosis | - | - | - | - | - | - | - | - | - | - | - | - | |||||
| Diagnosis (ref = hematological) | - | - | - | - | - | - | - | - | - | ||||||||
| CNS tumor | - | - | - | - | - | - | - | - | - | - | - | - | |||||
| Solid tumor | - | - | - | - | - | - | - | - | - | - | - | - | |||||
| Recurrence | - | - | - | - | - | - | - | - | - | 3.11 | [0.95;10.22] | 0.062 | |||||
| Surgery | - | - | - | - | - | - | - | - | - | - | - | - | |||||
| Chemotherapy | - | - | - | - | - | - | - | - | - | - | - | - | |||||
| Radiotherapy | 0.52 | [0.23;1.22] | 0.135 | - | - | - | - | - | - | - | - | - | |||||
| Psychosocial | |||||||||||||||||
| PedsQL-YA Physical Functioning | - | - | - | 1.00 | [0.97;1.03] | 0.978 | 1.01 | [0.98;1.04] | 0.499 | 0.92 | [0.96;1.01] | 0.187 | |||||
| PedsQL-YA Social Functioning | - | - | - | 0.96 | [0.93;0.99] | 0.005 | 0.96 | [0.93;0.99] | 0.012 | 1.00 | [0.98;1.03] | 0.937 | |||||
| PedsQL-YA Work/School Functioning | - | - | - | 0.98 | [0.96;1.01] | 0.247 | 0.98 | [0.95;1.01] | 0.114 | 1.00 | [0.97;1.02] | 0.511 | |||||
| HADS (sub)clinical anxiety (≥ 8) | 3.61 | [1.08;12.15] | 0.038 | 1.54 | [0.59;3.99] | 0.378 | 2.44 | [0.96;6.23] | 0.061 | 1.76 | [0.70;4.42] | 0.231 | |||||
| HADS (sub)clinical depression (≥ 8) | - | - | - | 0.48 | [0.12;1.98] | 0.312 | 1.12 | [0.24;5.15] | 0.886 | 1.76 | [0.42;7.36] | 0.439 | |||||
| CIS-20R severe fatigue (≥ 35) | - | - | - | 2.31 | [0.92;5.83] | 0.075 | 1.42 | [0.57;3.55] | 0.455 | 1.00 | [0.40;2.48] | 1.0 | |||||
- Not included in model; the following variables were not included in any model: Time since diagnosis, diagnosis, surgery (yes/no), chemotherapy (yes/no)
aYACCS with any need for support (%, N)
Abbreviations: YACCS Young Adult Childhood Cancer Survivor; CNS central nervous system; PedsQL-YA Pediatric Quality of Life–Young Adults; HADS Hospital Anxiety and Depression Scale; CIS-20R Individual Strength Revised