Fig. 9.

In silico immune response simulation of the mRNA vaccine construct. a Elevation of immunoglobulins at different concentrations of antigen, b Population of B lymphocytes (IgM, IgG1, and IgG2) after three injections, c Amount of helper T-lymphocytes population, d Helper T-cell count in the resting and active states, e Amount of Cytotoxic T-lymphocytes population, f Cytotoxic T-lymphocytes population in different states; resting and active, g Population of natural killer cells, h Population of macrophages, i Population of dendritic cells in the active and resting states, j Concentration of cytokines and interleukins with Simpson index