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. 2022 Jan 4;64(5):510–525. doi: 10.1007/s12033-021-00432-6

Table 2.

Selected four epitopes out of fifteen MHC II-binding peptides based on their high antigenicity and non-allergenic nature

Sl. No Epitope Percentile rank Allele Antigenicity Allergenicity
1 FGEVFNATRFASVYA 0.03

HLA-DPA1*01:03

DPB1*04:01

0.0415 Probable non-antigen Probable non-allergen
2 QSLLIVNNATNVVIK 0.01

HLA-DRB1*13:02

HLA-DRB1*04:01

0.4343 Probable antigen Probable non-allergen
3 KTQSLLIVNNATNVV 0.17 HLA-DRB3*02:02 0.6303 Probable antigen Probable allergen
4 NDPFLGVYYHKNNKS 9.30 HLA-DRB1*04:01 0.8199 Probable antigen Probable allergen
5 EVFNATRFASVYAWN 0.14

HLA-DPA1*01:03

DPB1*04:01

0.0832 Probable non-antigen Probable allergen
6 LLLQYGSFCTQLNRA 1.80

HLA-DRB1*04:05

DRB1*15:01

0.9471 Probable antigen Probable non-allergen
7 VVLSFELLHAPATVC 0.03 HLA-DRB1*01:01 0.8618 Probable antigen Probable non-allergen
8 CPFGEVFNATRFASV 0.18

HLA-DPA1*01:03

DPB1*04:01

0.2975 Probable non-antigen Probable non-allergen
9 GNYNYLYRLFRKSNL 5.00

HLA-DPA1*01:03

DPB1*04:01

0.1801 Probable non-antigen Probable non-allergen
10 GGNYNYLYRLFRKSN 3.60 HLA-DRB5*01:01 0.0207 Probable non-antigen Probable allergen
11 LSFELLHAPATVCGP 0.03 HLA-DRB1*01:01 0.5062 Probable antigen Probable allergen
12 SKTQSLLIVNNATNV 0.03 HLA-DRB1*13:02 0.6256 Probable antigen Probable allergen
13 SIIAYTMSLGAENSV 1.80 HLA-DPA1*02:01/DPB1*14:01 0.5691 Probable antigen Probable allergen
14 EGFNCYFPLQSYGFQ 2.20

HLA-DQA1*01:01

DQB1*05:01

0.5795 Probable antigen Probable allergen
15 TESIVRFPNITNLCP 0.69 HLA-DRB1*15:01 0.6128 Probable antigen Probable non-allergen