Table 2.
Independent Predictors of Hospitalization Requiring Airborne, Droplet, Contact, or Other Isolation for 4,599 Patients with Positive SARS-CoV-2 Tests (2/20/2020–11/8/2020)
| Unadjusted | Age and sex | Fully adjusted | ||||
|---|---|---|---|---|---|---|
| RR/95% CI | p>|z| | ARR/95% CI | p>|z| | ARR/95% CI | p>|z| | |
| 25-Hydroxy vitamin D, log-transformeda | 0.96 (0.84, 1.11) | 0.614 | 0.72 (0.63, 0.83) | <0.001 | 0.83 (0.72, 0.96) | 0.009 |
| Age at index dateb, years | 1.17 (1.15, 1.19) | <0.001 | 1.13 (1.10, 1.16) | <0.001 | ||
| Male | 1.30 (1.02, 1.64) | 0.031 | 1.14 (0.90, 1.45) | 0.263 | ||
| Race: non-Caucasian or unknown | 1.50 (1.34, 1.68) | <0.001 | ||||
| Ethnicity: Hispanic or Latinx | 1.18 (0.98, 1.42) | 0.080 | ||||
| Proportion of residents < federal poverty linec | 1.03 (1.00, 1.06) | 0.058 | ||||
| Body mass index, kg/m2 | 0.99 (0.98, 1.00) | 0.049 | ||||
| Diabetes (any) | 1.24 (1.11, 1.40) | <0.001 | ||||
| Cardiovascular disease (incl. hypertension) | 1.27 (1.12, 1.44) | <0.001 | ||||
| Obstructive sleep apnea | 1.12 (0.99, 1.27) | 0.062 | ||||
| Chronic obstructive pulmonary disease | 1.20 (1.06, 1.35) | 0.003 | ||||
| Cancer | 1.21 (1.08, 1.35) | 0.001 | ||||
| Chronic kidney disease | 1.44 (1.28, 1.62) | <0.001 | ||||
| Liver disease | 1.19 (1.02, 1.40) | 0.032 | ||||
| Human immunodeficiency virus | 1.21 (0.86, 1.72) | 0.276 | ||||
| Current or former smoker | 0.99 (0.89, 1.11) | 0.921 | ||||
| Non-alcohol drug dependence | 1.14 (0.90, 1.45) | 0.274 | ||||
| Alcohol dependence | 1.45 (1.22, 1.72) | <0.001 |
a25-Hydroxy Vitamin D, log-transformed as a continuous variable, was independently associated with decreased risk of hospitalization.
bRelative risk reflects 5 years increase in age.
cRelative risk reflects 5% increase in proportion of residents in patient ZIP code living below federal poverty line.