Table 4.
Independent Predictors of 60-day Mortality for 4,599 Patients with Positive SARS-CoV-2 Tests (2/20/2020–11/8/2020)
| Unadjusted | Age and sex | Fully adjusted | ||||
|---|---|---|---|---|---|---|
| RR/95% CI | p>|z| | ARR/95% CI | p>|z| | ARR/95% CI | p>|z| | |
| 25-Hydroxy vitamin D, log-transformeda | 1.09 (0.85, 1.40) | 0.495 | 0.61 (0.47, 0.79) | <0.001 | 0.65 (0.50, 0.84) | 0.001 |
| Age at index dateb, years | 1.47 (1.41, 1.52) | <0.001 | 1.44 (1.37, 1.51) | <0.001 | ||
| Male | 1.53 (0.88, 2.65) | 0.133 | 1.28 (0.73, 2.23) | 0.391 | ||
| Race: non-Caucasian or unknown | 1.23 (0.99, 1.53) | 0.059 | ||||
| Ethnicity: Hispanic or Latinx | 0.94 (0.63, 1.39) | 0.752 | ||||
| Proportion of residents < federal poverty linec | 1.00 (0.94, 1.05) | 0.875 | ||||
| Body mass index, kg/m2 | 1.00 (0.98, 1.02) | 0.979 | ||||
| Diabetes (any) | 1.42 (1.15, 1.76) | 0.001 | ||||
| Cardiovascular disease (incl. hypertension) | 1.30 (1.03, 1.63) | 0.026 | ||||
| Obstructive sleep apnea | 1.03 (0.82, 1.29) | 0.780 | ||||
| Chronic obstructive pulmonary Disease | 1.22 (0.99, 1.50) | 0.067 | ||||
| Cancer | 1.08 (0.88, 1.33) | 0.458 | ||||
| Chronic kidney disease | 1.64 (1.33, 2.01) | <0.001 | ||||
| Liver disease | 1.08 (0.76, 1.52) | 0.669 | ||||
| Human immunodeficiency virus | 0.63 (0.16, 2.53) | 0.513 | ||||
| Current or former smoker | 1.06 (0.86, 1.32) | 0.573 | ||||
| Non-alcohol drug dependence | 1.02 (0.57, 1.83) | 0.938 | ||||
| Alcohol dependence | 1.36 (0.91, 2.04) | 0.137 |
a25-Hydroxy vitamin D, log-transformed as a continuous variable, was independently associated with decreased risk of 60-day mortality.
bRelative risk reflects 5 years increase in age.
cRelative risk reflects 5% increase in proportion of residents in patient ZIP code living below federal poverty line.