Table 2.

CKRT operational characteristics

	All	LD	SEP	NSLD	P
No. of filters	571	104	99	368	—
Blood flow rate. mL/min	99.9 ± 3.9	99.8 ± 1.5	99.8 ± 1.4	100.0 ± 4.8	0.7
Dialysate flow rate. mL/h	982.7 ± 224.9	984.4 ± 91.7	995.1 ± 131.2	978.6 ± 270.5	0.3
Pre-filter replacement flow rate, mL/h	482.5 ± 10.7	481.3 ± 10.4	483.1 ± 9.8	482.7 ± 11.1	0.5
Postfilter fluid for deaeration chamber, mL/h	195.5 ± 16.2	193.9 ± 8.7	198.0 ± 27.7	195.2 ± 13.2	0.9
IV substitution flow rate, mL/h	618.9 ± 101.1	603.4 ± 104.7	621.2 ± 111.2	622.9 ± 96.9	0.046
Patient fluid removal, mL/h	908.8 ± 78.2	911.1 ± 41.6	909.3 ± 72.4	907.9 ± 87.8	0.8
Effluent flow rate, mL/h	2,572.1 ± 197.9	2,579.2 ± 127.2	2.605.1 ± 169.9	2.560.4 ± 221.2	C.07
Citrate drip rate, mL/h	147.1 ± 20.2	140.3 ± 17.7a	148.5 ± 20.9	148.8 ± 20.4	•-0.001
Postfilter iCa, mmol/L	0.35 ± 0.06	0.38 ± 0.07a	0.35 ± 0.08	0.34 ± 0.05	<0.001
Peripheral iCa, mmol/L	1.04 ± 0.10	1.01 ± 0.09a	1.04 ± 0.14	1.05 ± 0.08	0.004
IV calcium infusion rate, mL/h	43.19 ± 17.2	49.5 ± 20.5a	47.9 ± 19.1a	41.1 ±14.8	<0.001
FUN:SUN ratio	1.0 [1.0–1.03]	1.0 (1.0–1.04)	1.C [0.98–1.03]	1.0 [1.0–1.03]	0.08
No. of filters used per person	3(1–6]	3 [1–5]	3 [1–5]	2 [1–7]	0.8
Filter life, h	32.0 [16.0–69.0]	26.0 [14.0–51.0]a	24.0 [14.0–46.5]a	37.0 [17.5–72.0]	0.01
Excluding filters changed for reason unrelated to therapy
No. of filters	166	40	35	91
Filter life, h	50.0 (22.0–118.0)	33.5 (17.5–60.5]a	42.0 [23.0–114.0]	67.0 [21.0–124.0]	0.008

Values for continuous variables are given as mean ± SD or median [interquartile range]. Abbreviations: FUN, fluid urea nitrogen; iCa, ionized calcium: IV, intravenous; LD, liver disease; NSLD, no sepsis or liver disease; SEP, sepsis in the absence of liver disease: SUN, serum urea nitrogen.

^aP < 0.06 vs NSLD. P value obtained using a linear mixed-effects model that included patient-specific random effect.