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. 2021 Dec;11(6):e867–e875. doi: 10.1212/CPJ.0000000000001116

Figure 3. HSROC Curves for the Discriminative Ability of (A) CSF and (B) Circulating NfL to Differentiate APS From PD.

Figure 3

Each study is depicted as a hollow circle; the diameter of each circle corresponds to the respective weight given to each study. CSF NfL analysis is based on 7 studies: 363 patients with APS and 501 patients with PD; circulating NfL analysis is based on 4 studies: 214 patients with APS and 307 patients with PD. APS = atypical parkinsonian syndrome; HSROC = hierarchical summary receiver operating characteristic; NfL = neurofilament light chain; PD = Parkinson disease.