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. 2021 Oct 13;29(2):1061–1070. doi: 10.1245/s10434-021-10809-1

Table 3.

Multivariable associations for oncological outcomes

	n (%)^*	Cause-specific hazard		Subdistribution hazard
	n (%)^*	Univariate model	Multivariable model^**	Univariate model	Multivariable model^**
LBCR	2834 (97)	1.23 (0.67, 2.07), p = 0.470	1.33 (0.67, 2.39), p = 0.380	1.26 (0.89, 1.78), p = 0.194	1.40 (0.96, 2.05), p = 0.080
RBCR	3175 (72)	0.989 (0.41, 2.01), p = 0.978	0.731 (0.27, 1.59), p = 0.473	(0.62, 1.66), p = 0.473	0.78 (0.48, 1.27), p = 0.33
DDFS	2872 (253)	1.00 (0.58, 1.37), p = 0.699	0.84 (0.52, 1.31), p = 0.441	0.92 (0.61, 1.39), p = 0.710	0.84 (0.56, 1.27), p = 0.429
LBCR^***	2561 (78)		1.19 (0.53, 2.66), p = 0.677^***		1.25 (0.83, 1.87), p = 0.292^***

All models were corrected for the intracluster correlation of breast center

*Sample size of multivariable model

**Adjusted for subtype, pT, pN, invasive vs. noninvasive, and neoadjuvant therapy vs. adjuvant

***Additionally, adjusted for margin width (mm) and reoperation due to R1

LBCR local breast cancer recurrence rate; RBCR regional breast cancer recurrence rate; DDFS disease-free survival