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. 2021 Aug 20;41(1):19–31. doi: 10.1007/s10067-021-05819-z

Table 2.

Characteristics of the studies selected for the meta-analysis on the relapse rate

Author, year Assessment times (yrs) Patients (N) Type of study Recruitment period classification Criteria Criteria for relapse
Mørk C, 2020 [16] 1 174 R / P 2012–2017 Physician’s diagn C, L
Ayano M, 2020 [31] 1 32 R 2011–2017 Bird’s C, L, T
Do JG, 2018 [32] 1 34 R 2009–2017 ACR/EULAR C, L
Mackie SL, 2015 [24] 1 21 R NA Bird’s NS
Lee JH, 2013 [33] 1 39 R NA Bird’s C, L
Macchioni 2009 [34] 1 57 P NA Descriptive C, L
Weyand CM, 1999 [29] 1 27 P 1993–1996 Descriptive NS

Yrs, years. N, number. P, prospective. R, retrospective. NA, data not available. Rheum, rheumatology. Diagn., diagnosis. ACR, American College of Rheumatology. EULAR, European League Against Rheumatisms. C; clinical (reappearance or worsening of symptoms). L, laboratory (increased APRs). T, therapeutic (required increase of therapy)