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. 2021 Dec 21;12:789647. doi: 10.3389/fimmu.2021.789647

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Copyright © 2021 Lai, Zhang, Jiang, Mou, Li, Xi, Wu, Gao, Zhang, Chen, Huang, Li, Cai, Li, Zheng and Hu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Behavioral consequences of mice transplanted with fecal microbiota from untreated BD patients or healthy controls (BD mice, n=40; control mice, n=22). (A) OFT. The total distance (cm), central distance (cm), central time (s) and central time percentage (%), were measured (A1-A4). (B)FST. The immobility time (s), and immobility time percentage (%), were measured (B1, B2). All data were presented as means ± SEM. *p < 0.001 using independent t tests. FST, forced swimming test; OFT, open field test.